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Fluorescence complementation: an emerging tool for biological research

Paper ID Volume ID Publish Year Pages File Format Full-Text
37506 45363 2008 9 PDF Available
Title
Fluorescence complementation: an emerging tool for biological research
Abstract

Numerous technologies based on utilizing fluorescent proteins have been developed for biological research, and fluorescence complementation (FC) is a recent application for visualization of molecular events in living cells and organisms. Currently, ten fluorescent proteins have been demonstrated to support FC. Over the past five years, FC-based technologies have been developed to visualize a variety of molecular events, such as protein–protein interactions, post-translational modifications, protein folding, conformational changes, RNA–protein interactions, mRNA localization and DNA hybridization. In addition, FC has also been used for drug discovery. These applications are providing fascinating insights into many biological processes. Here, we review the principles and applications of FC technologies, discuss their current challenges and examine prospects for future advances.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 26, Issue 11, November 2008, Pages 622–630
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us