fulltext.study @t Gmail

Production of biofuels and biochemicals: in need of an ORACLE

Paper ID Volume ID Publish Year Pages File Format Full-Text
37534 45367 2010 7 PDF Available
Title
Production of biofuels and biochemicals: in need of an ORACLE
Abstract

The engineering of cells for the production of fuels and chemicals involves simultaneous optimization of multiple objectives, such as specific productivity, extended substrate range and improved tolerance – all under a great degree of uncertainty. The achievement of these objectives under physiological and process constraints will be impossible without the use of mathematical modeling. However, the limited information and the uncertainty in the available information require new methods for modeling and simulation that will characterize the uncertainty and will quantify, in a statistical sense, the expectations of success of alternative metabolic engineering strategies. We discuss these considerations toward developing a framework for the Optimization and Risk Analysis of Complex Living Entities (ORACLE) – a computational method that integrates available information into a mathematical structure to calculate control coefficients.

First Page Preview
Production of biofuels and biochemicals: in need of an ORACLE
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 28, Issue 8, August 2010, Pages 391–397
Authors
, ,
Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us