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Recent progress in developing FRET-based intracellular sensors for the detection of small molecule nutrients and ligands

Paper ID Volume ID Publish Year Pages File Format Full-Text
37567 45371 2006 4 PDF Available
Title
Recent progress in developing FRET-based intracellular sensors for the detection of small molecule nutrients and ligands
Abstract

Intracellular sensors for nutrients such as sugars, metabolic precursors and signaling ligands such as amino acids will help to elucidate the complex roles of these small molecules in biology. In this update, several recently developed sensors, originating from the Frommer laboratory, which combine bacterial periplasmic-binding protein-based specificity for ligand targeting with fluorescent protein-derived resonance energy transfer for signal transduction are reviewed. The insight gained from designing these sensors, along with the preliminary results gathered from their first application, serve to illustrate the impact that they can have on improving our fundamental understanding of biology.

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Recent progress in developing FRET-based intracellular sensors for the detection of small molecule nutrients and ligands
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 24, Issue 12, December 2006, Pages 539–542
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us