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The ribosome as a drug target

Paper ID Volume ID Publish Year Pages File Format Full-Text
37585 45373 2006 3 PDF Available
Title
The ribosome as a drug target
Abstract

The elucidation of the crystal structure of the ribosome and its subunits has dramatically increased our understanding of this organelle and the molecular interactions that determine its functional capabilities. Two recent publications, one on the structure of the bacterial ribosome at 3.5 Å resolution and one on the identification of functionally relevant sites within the small subunit rRNA, illustrate the importance of interdisciplinary approaches in exploiting the ribosome as a drug target.

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The ribosome as a drug target
Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 24, Issue 4, April 2006, Pages 145–147
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering