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Biomimetic approaches to protein and gene delivery for tissue regeneration

Paper ID Volume ID Publish Year Pages File Format Full-Text
37619 45376 2006 7 PDF Available
Title
Biomimetic approaches to protein and gene delivery for tissue regeneration
Abstract

Novel therapeutic strategies that promote wound healing seek to mimic the response of the body to wounding, to regenerate rather than repair injured tissues. Many synthetic or natural biomaterials have been developed for this purpose and are used to deliver wound therapeutics in a controlled manner that prevents unwanted and potentially harmful side-effects. Here, we review the natural and synthetic biomaterials that have been developed for protein and gene delivery to enhance tissue regeneration. Particular emphasis is placed on novel biomimetic materials that respond to environmental stimuli or release their cargo according to cellular demand. Engineering biomaterials to release therapeutic agents in response to physiologic signals mimics the natural healing process and can promote faster tissue regeneration and reduce scarring in severe acute or chronic wounds.

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Biomimetic approaches to protein and gene delivery for tissue regeneration
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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 24, Issue 7, July 2006, Pages 331–337
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us