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Drug discovery and sea hares: bigger is better

Paper ID Volume ID Publish Year Pages File Format Full-Text
37649 45380 2006 3 PDF Available
Title
Drug discovery and sea hares: bigger is better
Abstract

Traditionally, small molecules (<1 kDa) have dominated the study of the chemistry and chemical ecology of marine natural products. However, as reported in a recent publication, Yang and co-workers have isolated a 60-kDa antibacterial protein from the defensive secretions of the sea hare Aplysia californica. This protein, escapin, has been characterized as an l-amino acid oxidase with bacteriostatic and bacteriocidal activities. Their work highlights the largely untapped biomedical potential of marine organism-derived proteins and addresses the problems of supply associated with invertebrate natural products. It also leads to intriguing hypotheses about the ecological function(s) of the new protein.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 24, Issue 1, January 2006, Pages 1–3
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us