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Rationalizing membrane protein overexpression

Paper ID Volume ID Publish Year Pages File Format Full-Text
37692 45388 2006 8 PDF Available
Title
Rationalizing membrane protein overexpression
Abstract

Functional and structural studies of membrane proteins usually require overexpression of the proteins in question. Often, however, the ‘trial and error’ approaches that are mainly used to produce membrane proteins are not successful. Our rapidly increasing understanding of membrane protein insertion, folding and degradation means that membrane protein overexpression can be more rationalized, both at the level of the overexpression host and the overexpressed membrane protein. This change of mindset is likely to have a significant impact on membrane protein research.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 24, Issue 8, August 2006, Pages 364–371
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Online Support
Any Questions? feel free to contact us