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Engineered polymerases amplify the potential of ancient DNA

Paper ID Volume ID Publish Year Pages File Format Full-Text
37696 45390 2008 3 PDF Available
Title
Engineered polymerases amplify the potential of ancient DNA
Abstract

The generation of genomic data from mammoths and Neanderthals has reinvigorated discussion about whether extinct species could be brought back within the foreseeable future. However, post-mortem DNA decay rapidly reduces the number and quality of surviving DNA fragments, consequently increasing rates of sequencing error and forming a significant obstacle to accurate sequence reconstruction. Recent work has shown that it is possible to engineer a polymerase capable of using even highly damaged fragments as template sequences.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 26, Issue 6, June 2008, Pages 285–287
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us