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Catalytic efficiency and kcat/KM: a useful comparator?

Paper ID Volume ID Publish Year Pages File Format Full-Text
37756 45407 2007 3 PDF Available
Title
Catalytic efficiency and kcat/KM: a useful comparator?
Abstract

The ratio kcat/KM – often referred to as the ‘specificity constant’ – is a useful index for comparing the relative rates of an enzyme acting on alternative, competing substrates. However, an alternative description, ‘catalytic efficiency’, is frequently used, and on occasions misused, to compare the reactivity of two enzymes acting on the same substrate. Here, we highlight the pitfalls in using kcat/KM to compare the catalytic effectiveness of enzymes.

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Publisher
Database: Elsevier - ScienceDirect
Journal: - Volume 25, Issue 6, June 2007, Pages 247–249
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us