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Kinetic analysis on the production of polyhydroxyalkanoates from volatile fatty acids by Cupriavidus necator with a consideration of substrate inhibition, cell growth, maintenance, and product formation

Paper ID Volume ID Publish Year Pages File Format Full-Text
3988 202 2010 7 PDF Available
Title
Kinetic analysis on the production of polyhydroxyalkanoates from volatile fatty acids by Cupriavidus necator with a consideration of substrate inhibition, cell growth, maintenance, and product formation
Abstract

Volatile fatty acids (VFAs) could be utilized by Cupriavidus necator (previously named as Ralstonia eutropha) as its sole carbon and energy source for growth and polyhydroxyalkanoates (PHAs) synthesis. In such a biosynthesis, VFAs at a high concentration had an inhibition on cell growth and deteriorate metabolite production. In this work the kinetics of PHAs production and consumption of VFAs by C. necator with simultaneous considerations of substrate inhibition, cell growth, maintenance and product formation were explored. The growth of C. necator and production of PHAs were significantly affected by the initial VFAs concentration. The cell growth was inhibited under initial substrate-sufficient conditions, and the cell activities could be resumed with the consumption of VFAs in batch cultures. Experimental results verify that the model established in this work was able to appropriately describe the PHA production from VFAs by C. necator.

Keywords
Activated sludge; Biopolymers; Cupriavidus necator; Kinetics; Polyhydroxyalkanoates; Waste treatment
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Kinetic analysis on the production of polyhydroxyalkanoates from volatile fatty acids by Cupriavidus necator with a consideration of substrate inhibition, cell growth, maintenance, and product formation
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 49, Issue 3, 15 May 2010, Pages 422–428
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us