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Fe(OH)3 nano solid material: An efficient catalyst for regioselective ring opening of aryloxy epoxide with amines under solvent free condition

Paper ID Volume ID Publish Year Pages File Format Full-Text
40197 45845 2014 9 PDF Available
Title
Fe(OH)3 nano solid material: An efficient catalyst for regioselective ring opening of aryloxy epoxide with amines under solvent free condition
Abstract

•Catalysts Fe(OH)3, Fe3O4 and Fe2O3 were synthesized and characterized.•Among them Fe(OH)3 was effective in ring opening of aryloxy epoxides with amines.•The product β-amino alcohols were achieved in high yield (∼96%) in 10–360 min.•Drugs (S)-Propanolol and (S)-Naftopidil were prepared under solvent free condition.•The catalyst Fe(OH)3 was recycled several times successfully.

Iron hydroxide-Fe(OH)3 and iron oxides (Fe3O4 and Fe2O3) were successfully prepared and characterized. These materials were employed as efficient and environmentally benign heterogeneous catalysts for the epoxide ring opening reaction of various aryloxy, terminal and meso epoxides with aromatic and aliphatic amines under solvent free condition at room temperature. Out of these, nano-sized Fe(OH)3 (IH-1) showed better catalytic activity to give the product β-amino alcohols in excellent yield (up to ∼96%) and high regioselectivity in 10–360 min. The catalyst was successfully recycled and reused eight times with no loss in catalytic activity.

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Keywords
Nano-iron hydroxide; Heterogeneous catalyst; Aryloxy epoxide; Epoxide ring opening; Amino alcohol; Lewis and Brønsted acidity
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Fe(OH)3 nano solid material: An efficient catalyst for regioselective ring opening of aryloxy epoxide with amines under solvent free condition
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Publisher
Database: Elsevier - ScienceDirect
Journal: Applied Catalysis A: General - Volume 469, 17 January 2014, Pages 442–450
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us