fulltext.study @t Gmail

Facile open air oxidation of benzylic alcohols in distilled water by in situ made copper(II) complexes

Paper ID Volume ID Publish Year Pages File Format Full-Text
40758 45864 2012 10 PDF Available
Title
Facile open air oxidation of benzylic alcohols in distilled water by in situ made copper(II) complexes
Abstract

A highly efficient, selective and green catalytic protocol for open air oxidation of primary benzylic alcohols into aldehydes by in situ made N-isopropyl-3,5-di-tert-butylsalicylaldimine (HL3)–Cu(II) complexes and TEMPO (2,2,6,6-tetramethyl-piperidinyloxyl radical) is introduced herein. Distilled water as a solvent the reaction proceeds at 80 °C temperature without any auxiliarities such as base and/or co-solvent. For example, benzyl alcohol is quantitatively and selectively oxidized to benzaldehyde within a few hours under optimized reaction conditions [80 °C, open air, 0.3 mol% CuBr2, 2 mol% HL3, 3 mol% TEMPO and 5 mL of distilled water]. Under anaerobic conditions, the catalyst decomposes to a free ligand and Cu2O nanoparticles (diameter >50 nm) via anticipated Cu(I)-hydroxo complex. On the basis of these observations and deuteration studies, a plausible reaction mechanism is proposed for the catalytic system.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (70 K)Download as PowerPoint slideHighlights► A novel water tolerant catalytic system for alcohol oxidation has been developed. ► Various benzylic alcohols converted to aldehydes with high isolated yields. ► Very low loading of catalyst (0.3 mol%) and TEMPO (3 mol%) is required for efficient oxidation. ► Utilization of distilled water and open air compose a green protocol for the reactions.

Keywords
Oxidation; Alcohols; Copper; Open air; Distilled water
First Page Preview
Facile open air oxidation of benzylic alcohols in distilled water by in situ made copper(II) complexes
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Applied Catalysis A: General - Volume 449, 27 December 2012, Pages 153–162
Authors
, , , , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us