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Trace-level sensing of dopamine in real samples using molecularly imprinted polymer-sensor

Paper ID Volume ID Publish Year Pages File Format Full-Text
4274 218 2009 8 PDF Available
Title
Trace-level sensing of dopamine in real samples using molecularly imprinted polymer-sensor
Abstract

Induced-fit responsive dopamine (DA) imprinted polymer, poly (melamine-co-chloranil), was used as a suitable coating material for the modification of a hanging mercury drop electrode. The zwitterionic conformation of the imprinted polymer responded differential pulse, cathodic stripping voltammetric current, without any false-positive or false-negative contributions of non-specific sorptions, in aqueous environment of complex matrices. The limit of detection (3σ) of dopamine was found to be as low as 0.148 ng mL−1, by the proposed sensor that could be considered a sensitive marker of dopamine depletion in Parkinson's disease (PD).

Keywords
Bioseparations; Membrane; Mass-transfer; Affinity; Dopamine; Molecularly imprinted polymer
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Trace-level sensing of dopamine in real samples using molecularly imprinted polymer-sensor
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 44, Issues 2–3, 15 May 2009, Pages 232–239
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us