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Cellulose sulfuric acid as a bio-supported and recyclable solid acid catalyst for the one-pot three-component synthesis of α-amino nitriles

Paper ID Volume ID Publish Year Pages File Format Full-Text
43354 45965 2007 3 PDF Available
Title
Cellulose sulfuric acid as a bio-supported and recyclable solid acid catalyst for the one-pot three-component synthesis of α-amino nitriles
Abstract

α-Amino nitriles are synthesized by a one-pot three-component condensation reaction of amines, aldehydes and trimethylsilylcyanide in the presence of a catalytic amount of cellulose sulfuric acid as a bio-supported catalyst, in excellent yields with short reaction times at ambient temperature. The reaction work-up is simple and the catalyst can be easily separated from the product and reused in subsequent reactions.

Graphical abstractα-Amino nitriles are synthesized by a one-pot three-component condensation reaction of amines, aldehydes and trimethylsilylcyanide in the presence of a catalytic amount of cellulose sulfuric acid as a bio-supported catalyst, in excellent yields with short reaction times at ambient temperature. Figure optionsDownload full-size imageDownload as PowerPoint slide

Keywords
Cellulose sulfuric acid; Bio-supported catalyst; α-Amino nitriles; Trimethylsilylcyanide; Multi-component reaction
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Cellulose sulfuric acid as a bio-supported and recyclable solid acid catalyst for the one-pot three-component synthesis of α-amino nitriles
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Publisher
Database: Elsevier - ScienceDirect
Journal: Applied Catalysis A: General - Volume 331, 2007, Pages 149–151
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
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