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Unstructured model for batch cultures without pH control of Lactobacillus helveticus—Inhibitory effect of the undissociated lactic acid

Paper ID Volume ID Publish Year Pages File Format Full-Text
4702 239 2007 6 PDF Available
Title
Unstructured model for batch cultures without pH control of Lactobacillus helveticus—Inhibitory effect of the undissociated lactic acid
Abstract

During lactic acid fermentation, the positive effect of precultivating without pH control is now clearly established. At acidic pH, growth was inhibited. To account for this inhibition, the well-known Luedeking–Piret model was modified by introducing an additional term involving the undissociated form of the lactic acid, the main inhibitory species. The Henderson–Hasselbach equation was also considered in the model to describe the relationship between pH, also involved in growth inhibition, and both the dissociated and the undissociated forms of lactic acid. The model was found to describe satisfactory experimental growth and production data in a wide range of culture conditions. Indeed, whey permeate supplemented by a large range of nitrogen supplementations was considered and analysed, since the growth- and non-growth-associated part of the production can be easily deduced from the model. High supplementation of whey permeate, namely 20 g l−1 yeast extract and 10 g l−1 peptones, the usual seed culture supplementation, led to the main part of the lactic acid produced by a growth-associated mechanism (74%).

Keywords
Batch processing; Fermentation; Growth kinetics; Lactic acid; Modelling; Product inhibition
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Unstructured model for batch cultures without pH control of Lactobacillus helveticus—Inhibitory effect of the undissociated lactic acid
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 35, Issue 3, 1 August 2007, Pages 289–294
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us