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Candida rugosa lipase catalysed preparation of l-prolyl, l-phenylalanyl, l-tryptophanyl and l-histidyl esters of carbohydrates

Paper ID Volume ID Publish Year Pages File Format Full-Text
4845 250 2007 16 PDF Available
Title
Candida rugosa lipase catalysed preparation of l-prolyl, l-phenylalanyl, l-tryptophanyl and l-histidyl esters of carbohydrates
Abstract

l-Amino acyl (1–4) esters of carbohydrates (5–15) were synthesized through Candida rugosa lipase catalysis in non-polar solvent with yields in the range of 7–79%. In a reaction, involving unprotected and unactivated l-amino acids and carbohydrates, both monoesters (1-O-, 2-O-, 3-O-, 4-O-, 5-O-, 6-O- and 6′-O-) and diesters (1,6-di-O-, 2,5-di-O-, 2,6-di-O-, 3,6-di-O-, 4,6-di-O- and 6,6′-di-O-) were found to be formed in different proportions depending on the l-amino acids and carbohydrates employed. Among 80 individual esters synthesized by this procedure, 67 are being reported for the first time.

Keywords
Amino acyl esters of carbohydrates; Candida rugosa lipase; Monoesters; Diesters; Unprotected amino acids
First Page Preview
Candida rugosa lipase catalysed preparation of l-prolyl, l-phenylalanyl, l-tryptophanyl and l-histidyl esters of carbohydrates
Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 34, Issue 1, April 2007, Pages 28–43
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering