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Au(I)-catalyzed domino intramolecular cyclization for the synthesis of 2,4-disubstituted pyrimidines

Paper ID Volume ID Publish Year Pages File Format Full-Text
49411 46741 2016 4 PDF Available
Title
Au(I)-catalyzed domino intramolecular cyclization for the synthesis of 2,4-disubstituted pyrimidines
Abstract

•Au-catalyzed domino reactions•An efficient route for synthesis of 2,4-disubstituted pyrimidines•Formation of C–C and C–N bond via intramolecular cyclization

An efficient Au-catalyzed domino intramolecular cyclization reaction has been developed for the construction of pyrimidine derivatives from ynals and amidines at room temperature for 3 h. This transformation provides a new method for the formation of C–C and C–N bonds via intramolecular cyclization.

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Keywords
Pyrimidines; Gold; Domino reaction; Synthesis; Intramolecular cyclization
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Au(I)-catalyzed domino intramolecular cyclization for the synthesis of 2,4-disubstituted pyrimidines
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Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Communications - Volume 73, 5 January 2016, Pages 109–112
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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