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Analysis of the transient response of a CSTR containing immobilized enzyme particles: Part II. Minimum existence criterion and determination of substrate effective diffusivity and main reaction rate constant

Paper ID Volume ID Publish Year Pages File Format Full-Text
4948 261 2007 10 PDF Available
Title
Analysis of the transient response of a CSTR containing immobilized enzyme particles: Part II. Minimum existence criterion and determination of substrate effective diffusivity and main reaction rate constant
Abstract

A minimum existence criterion in the transient response of the bulk substrate concentration in a CSTR containing immobilized enzyme (IMEs) in porous solid supports has been obtained from simulation results using several kinetic expressions for the main reaction and the enzyme deactivation reaction. A simple method for the determination of the substrate effective diffusivity and the reaction rate constant is also presented, and applied to the decomposition of hydrogen peroxide, that reacts in a CSTR that contains silica–alumina porous catalyst particles, in which horseradish peroxidase enzyme had been previously immobilized.

Keywords
Transient response; Simulation; Bioreactors; Multiphase reactors; Parameter identification; Immobilized enzyme particles
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Analysis of the transient response of a CSTR containing immobilized enzyme particles: Part II. Minimum existence criterion and determination of substrate effective diffusivity and main reaction rate constant
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biochemical Engineering Journal - Volume 33, Issue 2, February 2007, Pages 116–125
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us