fulltext.study @t Gmail

Simple and efficient CuI/PEG-400 system for hydroxylation of aryl halides with potassium hydroxide

Paper ID Volume ID Publish Year Pages File Format Full-Text
50320 46789 2011 3 PDF Available
Title
Simple and efficient CuI/PEG-400 system for hydroxylation of aryl halides with potassium hydroxide
Abstract

This work reports a simple and efficient CuI/PEG-400 system for hydroxylation of aryl halides with potassium hydroxide. This protocol offers a direct transformation of aryl iodides or bromides to substituted phenols in great diversity. A very wide variety of functional groups are tolerated on aryl halides partners such as carboxyl, aldehyde and hydroxyl group.

Graphical abstractThis work reports a simple and efficient CuI/PEG-400 system for hydroxylation of aryl halides with potassium hydroxide. This protocol offers a direct transformation of aryl iodides or bromides to substituted phenols in excellent yields.Figure optionsDownload full-size imageDownload as PowerPoint slideResearch Highlights► Copper-catalyzed hydroxylation of aryl halides and potassium hydroxide was studied. ► Direct transformation of aryl iodides or bromides to substituted phenols with excellent yields. ► A very wide variety of functional groups is tolerated on aryl halides partners.

Keywords
Copper; Aryl halides; Hydroxylation; PEG-400
First Page Preview
Simple and efficient CuI/PEG-400 system for hydroxylation of aryl halides with potassium hydroxide
Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Communications - Volume 12, Issue 15, 15 September 2011, Pages 1463–1465
Authors
, , , ,
Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis