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A metal free, eco-friendly protocol for the synthesis of 2,3-dihydro-1H-perimidines using commercially available Amberlyst 15 as a catalyst

Paper ID Volume ID Publish Year Pages File Format Full-Text
50661 46806 2014 5 PDF Available
Title
A metal free, eco-friendly protocol for the synthesis of 2,3-dihydro-1H-perimidines using commercially available Amberlyst 15 as a catalyst
Abstract

•Amberlyst-15 is inexpensive, commercially available, and environmentally benign.•The protocol is selective for aryl-alkyl and dialkyl ketones.•Reaction proceeds in compared to shorter period with good yield of desired product.

An efficient protocol has been developed to synthesize various dihydro-1H-perimidine derivatives using commercially available Amberlyst-15 as a catalyst. Dihydro-1H-perimidine derivatives are potential candidates for pharmaceutical and high tech applications. The conspicuous features of this protocol are short reaction time, compared to higher product yield, easy recovery, reusability and regeneration of catalyst. The reaction was successfully scaled up to gram level, which reflects the practicability of the present protocol.

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Keywords
Amberlyst-15; β-Keto amide; 2,3-Dihydro-1H-perimidine; Ketone; Naphthalene-1,8-diamineKWOLFJPFCHCOCG-UHFFFAOYSA-N; YQYGPGKTNQNXMH-UHFFFAOYSA-N; BUZYGTVTZYSBCU-UHFFFAOYSA-N; NTPLXRHDUXRPNE-UHFFFAOYSA-N; GNKZMNRKLCTJAY-UHFFFAOYSA-N; XSAYZAUNJMRRIR-UHFFFAOYS
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A metal free, eco-friendly protocol for the synthesis of 2,3-dihydro-1H-perimidines using commercially available Amberlyst 15 as a catalyst
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Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Communications - Volume 57, 5 December 2014, Pages 138–142
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us