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Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy

Paper ID Volume ID Publish Year Pages File Format Full-Text
5227 352 2015 6 PDF Available
Title
Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy
Abstract

This paper presents the usefulness of perfusion computed tomography (pCT) in the diagnosis of diabetic pulmonary microangiopathy. Our previous works have shown that perfusion parameters are useful in the diagnosis of diabetic pulmonary microangiopathy. We are looking for such measurements and perfusion parameters that provide the most accurate diagnosis. Two types of comparison were made based on the results of clinical trials: non-diabetic vs. diabetic and diabetes without microangiopathy vs. diabetes with microangiopathy. Our studies have shown that PS (permeability surface) is only perfusion parameter statistically significant. In certain regions of interest logistic regression as a classifier produces very good results in diagnosing lung microangiopathy: sensitivity Sens = 89% and excellent specificity Spec = 100%. The results were obtained on the base of measurements taken from 23 subjects. These results were compared with results reported in the literature and based on diffusion capacity and spirometry measurements and modeling. None of the previous results was as good as those obtained using the PS and logistic regression for binary classification.

Keywords
Chest perfusion computed tomography; pCT; Pulmonary microangiopathy; Diabetes mellitus; Lung
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Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biocybernetics and Biomedical Engineering - Volume 35, Issue 1, 2015, Pages 68–73
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
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Full-text PDF Download
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Any Questions? feel free to contact us