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Efficient synthesis of β-amino alcohols by regioselective ring-opening of epoxides with anilines catalyzed by sulfated zirconia under solvent-free conditions

Paper ID Volume ID Publish Year Pages File Format Full-Text
52283 46867 2008 5 PDF Available
Title
Efficient synthesis of β-amino alcohols by regioselective ring-opening of epoxides with anilines catalyzed by sulfated zirconia under solvent-free conditions
Abstract

The catalytic efficacy of sulfated zirconia was investigated towards the opening of epoxide rings by aromatic amines under solvent-free conditions to selectively synthesize various β-amino alcohols with high regioselectivity. Interestingly, the SO42−/ZrO2 catalyst was found to exhibit an excellent catalytic activity for the title reaction. Various advantages associated with this novel and environmental friendly protocol include, solvent-free conditions, short reaction times, high product yields, simple workup procedure, and easy recovery and reusability of the catalyst.

Keywords
Epoxides ring-opening; Regioselectivity; β-Amino alcohols; Solvent-free; Sulfated zirconia; Aromatic amines
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Efficient synthesis of β-amino alcohols by regioselective ring-opening of epoxides with anilines catalyzed by sulfated zirconia under solvent-free conditions
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Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Communications - Volume 9, Issue 5, 20 March 2008, Pages 950–954
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us