Efficient Knoevenagel condensation catalyzed by cyclic guanidinium lactate ionic liquid as medium
As a reaction medium, cyclic guanidinium lactate ionic liquid can catalyze the Knoevenagel condensation of one of aromatic aldehydes with each of active methylene compounds at room temperature in a high yield of over 90% within just 1–7 min. At the same time, the work-up procedure is very simple and the products are not needed to be further purified. The ionic liquid can be easily reused without activity loss.
Journal: Catalysis Communications - Volume 8, Issue 2, February 2007, Pages 115–117