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HBF4-catalyzed Biginelli reaction: One-pot synthesis of dihydropyrimidin-2(1H)-ones under solvent-free conditions

Paper ID Volume ID Publish Year Pages File Format Full-Text
52292 46868 2007 4 PDF Available
Title
HBF4-catalyzed Biginelli reaction: One-pot synthesis of dihydropyrimidin-2(1H)-ones under solvent-free conditions
Abstract

An efficient synthesis of dihydropyrimidinones from the aldehyde, 1,3-dicarbonyl compound and urea (thiourea) under solvent-free conditions, using fluoroboric acid as the catalyst, is described. Compared with the classical Biginelli reaction conditions, this new protocol has the advantage of high yields, short reaction time and simplicity in the experimental procedure.

Keywords
Biginelli reaction; Fluoroboric acid; Solvent-free; Dihydropyrimidin-2(1H)-ones
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HBF4-catalyzed Biginelli reaction: One-pot synthesis of dihydropyrimidin-2(1H)-ones under solvent-free conditions
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Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Communications - Volume 8, Issue 2, February 2007, Pages 123–126
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us