A simple, efficient and green procedure for Knoevenagel reaction in [MMIm][MSO4] ionic liquid
The Knoevenagel reaction between aryl aldehydes and malononitrile proceeds efficiently in high yield at room temperature with 1,3-dimethylimidazolium methyl sulfate as solvent and glycine as catalyst. Work-up is very simple and the products do not need to be purified. A recycling study confirmed that the solvent can be reused multiple times without activity loss.
Journal: Catalysis Communications - Volume 9, Issue 8, 20 April 2008, Pages 1779–1781