fulltext.study @t Gmail

Aqueous-phase catalytic oxidation, transfer hydrogenation, reductive amination and hydration reactions

Paper ID Volume ID Publish Year Pages File Format Full-Text
54027 46993 2015 5 PDF Available
Title
Aqueous-phase catalytic oxidation, transfer hydrogenation, reductive amination and hydration reactions
Abstract

•Water-soluble copper catalyst for oxidation of alcohols, alkylarenes and alkynes.•Oppenauer-type oxidation catalyzed by water-soluble iridium catalyst.•Meerwein–Ponndorf–Verley-type reduction catalyzed by water-soluble rhodium catalyst.•Reductive amination catalyzed by water soluble palladium catalyst.•Hydration of nitriles to amides catalyzed by water-soluble rhodium catalyst.

As part of our work devoted to the synthesis of organic compounds using “green” processes, we developed several water-soluble catalysts that allow efficiently the synthesis of ketones, amines, alcohols and amides. CuCl2·2H2O combined to 2,2′-biquinoline-4,4′-dicarboxylic acid dipotassium salt (BQC) was reported as an active catalyst for the selective oxidation with TBHP of alcohols, alkylarenes and alkynes. We developed also successfully hydrogen transfer reactions. While [Ir(COD)Cl]2/BQC proved to be efficient for Oppenauer-type oxidation of secondary alcohols, [Rh(COD)Cl]2/P(m-C6H4SO3Na)3 (TPPTS) showed very good activities for Meerwein–Ponndorf–Verley-type reduction of ketones and aldehydes. Higher alkylated amines and amides were also synthesized respectively, by direct reductive amination of aldehydes with primary and secondary amines catalyzed by water soluble Pd(PhCN)2Cl2/BQC, and hydration of nitriles with [Rh(COD)Cl]2/TPPTS. Many of these catalytic systems are recycled with no significant loss of activity and the final products are isolated in easy manners.

Graphical abstractFigure optionsDownload full-size imageDownload high-quality image (168 K)Download as PowerPoint slide

Keywords
Water-soluble catalyst; Reductive amination; Oxidation; Transfer hydrogenation; Hydration; 2,2′-Biquinoline-4,4′-dicarboxylic acid dipotassium salt
First Page Preview
Aqueous-phase catalytic oxidation, transfer hydrogenation, reductive amination and hydration reactions
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us
Publisher
Database: Elsevier - ScienceDirect
Journal: Catalysis Today - Volume 247, 1 June 2015, Pages 177–181
Authors
,
Subjects
Physical Sciences and Engineering Chemical Engineering Catalysis
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us