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Novel processing of iron–manganese alloy-based biomaterials by inkjet 3-D printing ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
571 51 2013 11 PDF Available
Title
Novel processing of iron–manganese alloy-based biomaterials by inkjet 3-D printing ☆
Abstract

The present work provides an assessment of 3-D printed iron–manganese biodegradable scaffolds as a bone scaffold material. Iron-based alloys have been investigated due to their high strength and ability to slowly corrode. Current fabrications of Fe-based materials generate raw material which must be machined into their desired form. By using inkjet 3-D printing, a technique which generates complex, customizable parts from powders mechanically milled Fe–30Mn (wt.%) powder was directly processed into scaffolds. The 3-D printed parts maintained an open porosity of 36.3% and formed a mixed phase alloy of martensitic ε and austenitic γ phases. Electrochemical corrosion tests showed the 3-D printed Fe–Mn to desirably corrode significantly more rapidly than pure iron. The scaffolds exhibited similar tensile mechanical properties to natural bone, which may reduce the risk of stress shielding. Cell viability testing of MC3T3-E1 pre-osteoblast cells seeded directly onto the Fe–Mn scaffolds using the live/dead assay and with cells cultured in the presence of the scaffolds’ degradation products demonstrated good in vitro cytocompatibility compared to tissue culture plastic. Cell infiltration into the open pores of the 3-D printed scaffolds was also observed. Based on this preliminary study, we believe that 3-D printed Fe–Mn alloy is a promising material for craniofacial biomaterial applications, and represents an opportunity for other biodegradable metals to be fabricated using this unique method.

Keywords
Bone replacement material; 3-D inkjet printing; Biodegradable metal; Iron–manganese; Porous scaffold
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Novel processing of iron–manganese alloy-based biomaterials by inkjet 3-D printing ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 9, Issue 10, November 2013, Pages 8593–8603
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us