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Water-soluble Ag2S quantum dots for near-infrared fluorescence imaging in vivo

Paper ID Volume ID Publish Year Pages File Format Full-Text
6690 511 2012 6 PDF Available
Title
Water-soluble Ag2S quantum dots for near-infrared fluorescence imaging in vivo
Abstract

A one-step method for synthesizing water-soluble Ag2S quantum dots terminated with carboxylic acid group has been reported. The crystal structure and surface of the prepared Ag2S quantum dots were characterized. The prepared Ag2S quantum dots exhibited bright photoluminescence and excellent photostabilities. The photoluminescence emissions could be tuned from visible region to near-infrared (NIR) region (from 510 nm to 1221 nm). Ultra-small sized Ag2S nanoclusters were synthesized with high initial monomer concentration in the current system. The in vivo imaging experiments of nude mice showed that the NIR photoluminescence of the prepared Ag2S quantum dots could penetrate the body of mice. Compared to the conventional NIR quantum dots, the Ag2S quantum dots don't contain toxic elements to body (such as Cd and Pb), thus, the prepared Ag2S quantum dots could serve as excellent NIR optical imaging probes and would open the opportunity to study nanodiagnostics and imaging in vivo.

Keywords
Fluorescence; Nanocrystals; Near-infrared; In vivo imaging; Silver sulfide
First Page Preview
Water-soluble Ag2S quantum dots for near-infrared fluorescence imaging in vivo
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 33, Issue 20, July 2012, Pages 5130–5135
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering