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Cubic sub-20 nm NaLuF4-based upconversion nanophosphors for high-contrast bioimaging in different animal species ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
6951 525 2012 10 PDF Available
Title
Cubic sub-20 nm NaLuF4-based upconversion nanophosphors for high-contrast bioimaging in different animal species ☆
Abstract

A new upconversion luminescence (UCL) nanophosphors based on host matrix of cubic NaLuF4 with bright luminescence have been synthesized by a solvothermal method, facilitate the nanocrystals potential candidates for imaging in vivo, especially large-animals. The sub-20 nm NaLuF4 co-doped Yb3+ and Er3+ (Tm3+) showed about 10-fold stronger UCL emission than that of corresponding hexagonal NaYF4-based nanocrystals with a 20 nm diameter. Near-infrared to near-infrared (NIR-to-NIR) UCL emission of PAA-coated NaLuF4:20%Yb,1%Tm (PAA-LuTm) can penetrate >1.5 cm tissue of pork with high contrast. Based on super-strong UCL emission and deep penetration, PAA-LuTm as optical bioprobe has been demonstrated by in vivo UCL imaging of a normal black mouse, even rabbit with excellent signal-to-noise ratio. Furthermore, such cubic NaLuF4-based nanophosphor was applied in lymph node imaging of live Kunming mouse with rich white fur.

Keywords
Upconversion nanophosphors; NaLuF4; Large-animal imaging; Upconversion luminescence imaging
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Cubic sub-20 nm NaLuF4-based upconversion nanophosphors for high-contrast bioimaging in different animal species ☆
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 33, Issue 14, May 2012, Pages 3733–3742
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us