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Advantages of RGD peptides for directing cell association with biomaterials ☆

Paper ID Volume ID Publish Year Pages File Format Full-Text
7525 555 2011 6 PDF Available
Title
Advantages of RGD peptides for directing cell association with biomaterials ☆
Abstract

Despite many years of in vitro research confirming the effectiveness of RGD in promoting cell attachment to a wide variety of biomaterials, animal studies evaluating tissue responses to implanted RGD-functionalized substrates have yielded more variable results. The goals of this report are to present some of the reasons why cell culture studies may not always reliably predict in vivo responses, and more importantly, to highlight potential applications that may benefit from the use of RGD peptides.

Keywords
RGD; Integrin; Extracellular matrix; Tissue regeneration; Cell adhesion
First Page Preview
Advantages of RGD peptides for directing cell association with biomaterials ☆
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 32, Issue 18, June 2011, Pages 4205–4210
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering