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Assessing the corrosion of biodegradable magnesium implants: A critical review of current methodologies and their limitations

Paper ID Volume ID Publish Year Pages File Format Full-Text
765 63 2012 12 PDF Available
Title
Assessing the corrosion of biodegradable magnesium implants: A critical review of current methodologies and their limitations
Abstract

Magnesium (Mg) and its alloys have been intensively studied as biodegradable implant materials, where their mechanical properties make them attractive candidates for orthopaedic applications. There are several commonly used in vitro tests, from simple mass loss experiments to more complex electrochemical methods, which provide information on the biocorrosion rates and mechanisms. The various methods each have their own unique benefits and limitations. Inappropriate test setup or interpretation of in vitro results creates the potential for flawed justification of subsequent in vivo experiments. It is therefore crucial to fully understand the correct usages of each experiment and the factors that need to be considered before drawing conclusions. This paper aims to elucidate the main benefits and limitations for each of the major in vitro methodologies that are used in examining the biodegradation behaviour of Mg and its alloys.

Keywords
Magnesium; In vitro; Biocorrosion; Biomaterial; Polarization
First Page Preview
Assessing the corrosion of biodegradable magnesium implants: A critical review of current methodologies and their limitations
Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 8, Issue 3, March 2012, Pages 925–936
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering