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Sub-lamellar microcracking and roles of canaliculi in human cortical bone

Paper ID Volume ID Publish Year Pages File Format Full-Text
778 63 2012 8 PDF Available
Title
Sub-lamellar microcracking and roles of canaliculi in human cortical bone
Abstract

Bone is a tough biological material. It is generally accepted that bone’s toughness arises from its unique hierarchical structure, which in turn facilitates distributed microcracking prior to fracture. Yet, there has been limited progress on the detailed roles of the structural elements in the microcracking process. The present study examines the structure–microcracking relations at the lamellar and sub-lamellar levels of human cortical bone subjected to compressive loading. Laser scanning confocal microscopy revealed a clear influence of the local structure and porosity of the Haversian systems’ lamellae on microcrack development. In particular, crack initiation and growth under transverse compression were associated with stress concentration at canaliculi. Later stages of microcracking showed extensive sub-lamellar cracks forming cross-hatched patterns and regularly spaced 0.5–1.7 μm apart. The density, size and regularity of the crack patterns suggest enhanced inelastic deformation capacity through cracking control at the level of mineralized collagen fibril bundles. The present study thus improves the current understanding of the nature of inelastic deformation and microcracking in bone and further suggests that bone’s resistance to fracture is achieved through microcrack control at multiple length scales.

Keywords
Bone fracture; Cortical bone; Inelastic deformation; Microcracking; Canaliculi
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Sub-lamellar microcracking and roles of canaliculi in human cortical bone
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 8, Issue 3, March 2012, Pages 1093–1100
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us