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Poly(glycerol-dodecanoate), a biodegradable polyester for medical devices and tissue engineering scaffolds

Paper ID Volume ID Publish Year Pages File Format Full-Text
8303 585 2009 6 PDF Available
Title
Poly(glycerol-dodecanoate), a biodegradable polyester for medical devices and tissue engineering scaffolds
Abstract

In this paper we describe the mechanical and biological features of a thermosetting polyester synthesized from glycerol and dodecanedioic acid named Poly-Glycerol-Dodecanoate (PGD). This polymer shows a glass transition temperature (Tg) around 32 °C, and this accounts for its mechanical properties. At room temperature (21°) PGD behaves like a stiff elastic-plastic material, while at body temperature (37 °C), it shows a compliant non-linear elastic behavior. Together with biodegradability and biocompatibility PGD has distinct shape memory features. After the polymer is cured, no matter what the final configuration is, we can recover the original shape by heating PGD to temperatures of 32 °C and higher. The mechanical properties together with biocompatibility/biodegradability and shape memory features make PGD an attractive polymer for biomedical applications.

Keywords
Biopolymer; Soft tissue engineering; Polyester; Shape memory; Smart polymers
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Poly(glycerol-dodecanoate), a biodegradable polyester for medical devices and tissue engineering scaffolds
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 30, Issue 33, November 2009, Pages 6479–6484
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us