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Resorption of monetite granules in alveolar bone defects in human patients

Paper ID Volume ID Publish Year Pages File Format Full-Text
8563 598 2010 8 PDF Available
Title
Resorption of monetite granules in alveolar bone defects in human patients
Abstract

Bone grafting is often required to restore mandibular or maxillary bone volume prior to prosthetic tooth root implantation. Preclinical animal models are often used to study the in vivo properties of new bone graft products designed for human use. Although animal studies may offer valuable data regarding bioperformance, materials do not necessarily perform the same in human patients. In this study we implanted bovine hydroxyapatite (BH), a widely used porous apatite granule, and dicalcium phosphate anhydrous (monetite) granules, bilaterally in human patients post extraction alveolar sockets. After six months, histomorphometrical analysis of the biopsies revealed that the amount of bone regenerated with monetite (59.5 ± 13%) was significantly higher than that obtained with BH (33.1% ± 4.9), while the amount of unresorbed graft was higher in the sockets treated with BH (37.8 ± 6.1) than in those implanted with monetite (25.8 ± 14.3). Resorption of calcium phosphate ceramics is discussed by applying the Hixon–Crowell dissolution model.

Keywords
Monetite; Human; Resorption; Bovine hydroxyapatite; Histomorphometry; Histology
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Resorption of monetite granules in alveolar bone defects in human patients
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 31, Issue 10, April 2010, Pages 2762–2769
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us