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Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO2 laser cladding

Paper ID Volume ID Publish Year Pages File Format Full-Text
893 68 2011 12 PDF Available
Title
Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO2 laser cladding
Abstract

Three-dimensional bioactive glass implants were produced by rapid prototyping based on laser cladding without using moulds. CO2 laser radiation was employed to melt 45S5 and S520 bioactive glass particles and to deposit the material layer by layer following a desired geometry. Controlled thermal input and cooling rate by fine tuning of the processing parameters allowed the production of crack-free fully dense implants. Microstructural characterization revealed chemical composition stability, but crystallization during processing was extensive when 45S5 bioactive glass was used. Improved results were obtained using the S520 bioactive glass, which showed limited surface crystallization due to an expanded sintering window (the difference between the glass transition temperature and crystallization onset temperature). Ion release from the S520 implants in Tris buffer was similar to that of amorphous 45S5 bioactive glass prepared by casting in graphite moulds. Laser processed S520 scaffolds were not cytotoxic in vitro when osteoblast-like MC3T3-E1 cells were cultured with the dissolution products of the glasses; and the MC3T3-E1 cells attached and spread well when cultured on the surface of the materials.

Keywords
Bioactive glass; Rapid prototyping; Laser cladding; Cranioplasty; Tissue engineering
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Three-dimensional bioactive glass implants fabricated by rapid prototyping based on CO2 laser cladding
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Publisher
Database: Elsevier - ScienceDirect
Journal: Acta Biomaterialia - Volume 7, Issue 9, September 2011, Pages 3476–3487
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us