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Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods

Paper ID Volume ID Publish Year Pages File Format Full-Text
8931 610 2009 9 PDF Available
Title
Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods
Abstract

Gold nanorods coated with a multiplex component, namely Au2S/AuAgS coated gold nanorods, are produced without precipitation and aggregation among the nanorods. Both the thickness of the shell and size of the core can be readily controlled by this technique allowing one to tune the plasmon resonance of the nanocomposites over a range of several hundred nanometers. These Au2S/AuAgS coated gold nanorods exhibit interesting optical properties and are suitable for many biological sensing applications. Functionalization of the Au2S/AuAgS coated gold nanorods is achieved by manipulating the affinity between the Au2S/AuAgS and thiol compounds. Biomolecules can be covalently attached via the NH2 bond of the antibodies to the NHS-terminated nanorods. The longitudinal peaks of the Au2S/AuAgS coated gold nanorods are extremely sensitive to the refractive index changes induced by target binding, suggesting that they are excellent sensors for target-specific binding events and have the potential to achieve single-molecule sensitivity in microspectroscopy.

Keywords
Biological sensing; Nanorods; Functionalization; Au2S/AuAgS coated gold nanorods Core–shell nanostructure Optical properties
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Optical and biological sensing capabilities of Au2S/AuAgS coated gold nanorods
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 30, Issue 29, October 2009, Pages 5622–5630
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us