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The use of platelet-rich plasma in bone reconstruction therapy

Paper ID Volume ID Publish Year Pages File Format Full-Text
9030 615 2009 11 PDF Available
Title
The use of platelet-rich plasma in bone reconstruction therapy
Abstract

The use of platelet-rich plasma (PRP) in bone reconstruction therapy was introduced in the late 1990s. Since then, many scientists and clinicians have employed it in orthopaedic and oral surgeries. Unfortunately, studies that analyze the use of PRP are somewhat controversial as some conclude that the use of PRP may favor bone regeneration and others conclude that the use of PRP is irrelevant. By listing and analyzing the biological effect that each factor released by the activated platelets can have in bone regeneration, the present review answers the question of why PRP may be useful in bone reconstruction therapy. Subsequently, by examining the studies that have both successfully and unsuccessfully utilized PRP, it suggests how PRP might be used in order to achieve successful results in orthopaedic and dental bone reconstruction surgeries.

Keywords
Platelet-rich plasma; Dental surgery; Bone regeneration; Bone reconstruction therapy; Growth factors; Orthopaedic surgery
First Page Preview
The use of platelet-rich plasma in bone reconstruction therapy
Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 30, Issue 28, October 2009, Pages 4956–4966
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering