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The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles

Paper ID Volume ID Publish Year Pages File Format Full-Text
9528 634 2009 5 PDF Available
Title
The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles
Abstract

We report the formation of polysiloxane polymers containing embedded methylene blue and gold nanoparticles incorporated by a swell-encapsulation-shrink method. These polymers show significant antimicrobial activity against methicillin-resistant Staphylococcus aureus and Escherichia coli with up to a 3.5 log10 reduction in the viable count when exposed for 5 min to light from a low power 660 nm laser. The bacterial kill is due to the light-induced production of singlet oxygen and other reactive oxygen species by the methylene blue. Interestingly, the presence of 2 nm gold nanoparticles significantly enhanced the ability of the methylene blue to kill bacteria.

Keywords
Catheter; Hospital acquired infection; Polymer; Nanoparticle; Light-activated antimicrobial
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The antimicrobial properties of light-activated polymers containing methylene blue and gold nanoparticles
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 30, Issue 1, January 2009, Pages 89–93
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us