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Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents

Paper ID Volume ID Publish Year Pages File Format Full-Text
9662 641 2008 6 PDF Available
Title
Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents
Abstract

The majority of stent materials are not fully compatible with magnetic resonance imaging due to their ferromagnetic or paramagnetic compositions. This leads to image artifact which can obscure clinical data in the vicinity of the stent. An Nb–28Ta–3.5W–1.3Zr alloy has been developed specifically to provide reduced magnetic susceptibility and therefore reduce image artifact. This study reports on initial surface characterization, corrosion behaviour, endothelial cell response and MR image performance. Surface analysis confirms the presence of a niobium oxide with some tantalum oxide also present. Electrochemical corrosion testing demonstrates the oxide to be stable with no evidence of film breakdown. Leaching of metallic ions during a 60-day immersion test shows low levels of release, comparable to cobalt–chromium L605. A short term endothelial cell adhesion study shows that the Nb–28Ta–3.5W–1.3Zr may be similar to stainless steel for supporting cell growth. The MR artifact assessment shows that the material has significantly reduced artifact compared to stainless steel. In summary, results from this initial study show that the Nb–28Ta–3.5W–1.3Zr meets many on the criteria expected of a stent material and that improved MR imaging behaviour is also obtained.

Keywords
Magnetic resonance; Stent; Artifact; Niobium
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Characterization of an NbTaWZr alloy designed for magnetic resonance angiography compatible stents
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 29, Issue 34, December 2008, Pages 4540–4545
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us