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Movement of polymer microcarriers using a biomolecular motor

Paper ID Volume ID Publish Year Pages File Format Full-Text
9833 648 2010 6 PDF Available
Title
Movement of polymer microcarriers using a biomolecular motor
Abstract

This work enables polymer microcarriers to be transported on a motor protein coated substrate. The size of microencapsulation system- layered polymer capsules could be controlled through changing heating time during post-treatment. In this active biomimetic system, the microtubules act as shuttles that transport the attached polymer microcarriers. The velocity of the motility does not depend on size of the capsules but the fraction of mobile capsules depends on capsule size and biotinylation proportion of microtubule. The microtubule could also propel dextran-filled capsules to transport the internal components on the activated surface. The study integrates the artificial materials into kinesin-microtubule system and provides a potential use for straightforward and facile transport of polymer materials and fabrication of the hybrid microdevices for biochemical sensing and delivery applications.

Keywords
Biomolecular motor; Biomimetics; Assembly; Capsules; Polymeric materials; Kinesin
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Publisher
Database: Elsevier - ScienceDirect
Journal: Biomaterials - Volume 31, Issue 6, February 2010, Pages 1287–1292
Authors
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Subjects
Physical Sciences and Engineering Chemical Engineering Bioengineering
Get Full-Text Now
Don't Miss Today's Special Offer
Price was $35.95
You save - $31
Price after discount Only $4.95
100% Money Back Guarantee
Full-text PDF Download
Online Support
Any Questions? feel free to contact us